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Most Influential AMERICAN JOURNAL OF GASTROENTEROLOGY Papers

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AJG is published on behalf of the American College of Gastroenterology (ACG). As the leading clinical journal covering gastroenterology and hepatology, The American Journal of Gastroenterology (AJG) provides practical and professional support for clinicians dealing with the gastroenterological disorders seen most often in patients. Paper Digest Team analyze all papers published on AMERICAN JOURNAL OF GASTROENTEROLOGY in the past years, and presents the 10 most influential papers for each year (based on when the paper became available online). This ranking list is automatically constructed based upon citations from both research papers and granted patents, and will be frequently updated to reflect the most recent changes. To find the most influential papers from other conferences/journals, visit Best Paper Digest page. Note: the most influential papers may or may not include the papers that won the best paper awards. (Last updated on: 2021-05-23)

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TABLE 1: Most Influential AMERICAN JOURNAL OF GASTROENTEROLOGY Papers

Year Rank Paper Author(s)
2020 1 Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study
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Abstract: Since the outbreak of Coronavirus Disease 2019 (COVID-19) in December 2019, various digestive symptoms have been frequently reported in patients infected with the virus. In this …		 LEI PAN et. al.
2020 2 Digestive Symptoms in COVID-19 Patients With Mild Disease Severity: Clinical Presentation, Stool Viral RNA Testing, and Outcomes
IF:4   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
Abstract: Coronavirus disease 2019 (COVID-19) most commonly presents with respiratory symptoms, including cough, shortness of breath, and sore throat. However, digestive symptoms also occur …		 CHAOQUN HAN et. al.
2020 3 COVID-19 Disease With Positive Fecal and Negative Pharyngeal and Sputum Viral Tests
IF:3   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
 Lijuan Chen; Jianghua Lou; Yan Bai; Meiyun Wang;
2020 4 SARS-CoV-2 Gastrointestinal Infection Causing Hemorrhagic Colitis: Implications for Detection and Transmission of COVID-19 Disease
IF:3   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
 ALEXANDRE CARVALHO et. al.
2020 5 Complementary and Alternative Medicine for Functional Gastrointestinal Disorders
IF:3   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
Abstract: The relevance of functional gastrointestinal (GI) disorders and their impact on quality of life for many patients has become an increasingly important topic in gastroenterology. A …		 Jill K Deutsch; Joshua Levitt; David J Hass;
2020 6 Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update By The US Multi-Society Task Force on Colorectal Cancer
IF:3   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
 SAMIR GUPTA et. al.
2020 7 Increased Risk of COVID-19 Among Users of Proton Pump Inhibitors
IF:3   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
Abstract: Proton pump inhibitors (PPIs) increase the risk for enteric infections that is likely related to PPI-induced hypochlorhydria. Although the impact of acid suppression on severe …		 Christopher V Almario; William D Chey; Brennan M R Spiegel;
2020 8 ACG Clinical Guideline: Small Intestinal Bacterial Overgrowth
IF:3   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
Abstract: Small intestinal bacterial overgrowth is defined as the presence of excessive numbers of bacteria in the small bowel, causing gastrointestinal symptoms. This guideline statement …		 Mark Pimentel; Richard J Saad; Millie D Long; Satish S C Rao;
2020 9 COVID-19 Presenting As Acute Hepatitis
IF:3   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
 Praneet Wander; Marcia Epstein; David Bernstein;
2020 10 Lipase Elevation in Patients With COVID-19
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Abstract: Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and …		 JULIA MCNABB-BALTAR et. al.
2019 1 ACG Clinical Guideline: Ulcerative Colitis In Adults
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Abstract: Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the preferred approach to the management of adults with UC and represent the official …		 David T Rubin; Ashwin N Ananthakrishnan; Corey A Siegel; Bryan G Sauer; Millie D Long;
2019 2 Screening For Gastric Cancer
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 Antonio Ponzetto; Natale Figura;
2019 3 Fecal Microbiota Transplantation in Patients With Primary Sclerosing Cholangitis: A Pilot Clinical Trial
IF:3   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
Abstract: Primary sclerosing cholangitis (PSC) is a cholestatic liver disease with no effective medical therapies. A perturbation of the gut microbiota has been described in association …		 JESSICA R ALLEGRETTI et. al.
2019 4 A Treat-to-Target Update In Ulcerative Colitis: A Systematic Review
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Abstract: In 2015, the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) program proposed shifting the therapeutic focus on ulcerative colitis (UC) toward altering the …		 Ryan Ungaro; Jean-Frédéric Colombel; Trevor Lissoos; Laurent Peyrin-Biroulet;
2019 5 Evidence For Local And Systemic Immune Activation In Functional Dyspepsia And The Irritable Bowel Syndrome: A Systematic Review
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Abstract: Subtle histopathologic features such as eosinophilia and increased mast cells have been observed in functional gastrointestinal disorders (FGIDs), including functional dyspepsia …		 GRACE BURNS et. al.
2019 6 Efficacy Of Fecal Microbiota Transplantation In Irritable Bowel Syndrome: A Systematic Review And Meta-Analysis
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Abstract: Irritable bowel syndrome (IBS) is a common gastrointestinal condition with a heterogeneous pathophysiology. An altered gut microbiome has been identified in some IBS patients, and …		 DABO XU et. al.
2019 7 Prucalopride In Gastroparesis: A Randomized Placebo-Controlled Crossover Study
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Abstract: Prokinetics are considered the preferred treatment option for gastroparesis, but evidence of their efficacy is scarce. Prucalopride, a selective 5-hydroxytryptamine 4 receptor …		 FLORENCIA CARBONE et. al.
2019 8 Tenofovir Versus Entecavir For Hepatocellular Carcinoma Prevention In An International Consortium Of Chronic Hepatitis B
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Abstract: It is unclear whether entecavir (ETV) and tenofovir disoproxil fumarate (TDF) differ in their effectiveness for preventing hepatocellular carcinoma (HCC) in patients with chronic …		 YAO-CHUN HSU et. al.
2019 9 Patients’ Perceptions Of Proton Pump Inhibitor Risks And Attempts At Discontinuation: A National Survey
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Abstract: Little is known about how reports on the adverse effects of proton pump inhibitors (PPIs) impact patients’ perceptions of these drugs and medication use. We sought to determine …		 JACOB E KURLANDER et. al.
2019 10 ACG Clinical Guideline: Hereditary Hemochromatosis
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Abstract: Hereditary hemochromatosis (HH) is one of the most common genetic disorders among persons of northern European descent. There have been recent advances in the diagnosis, …		 Kris V Kowdley; Kyle E Brown; Joseph Ahn; Vinay Sundaram;
2018 1 ACG Clinical Guideline: Alcoholic Liver Disease
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Abstract: Alcoholic liver disease (ALD) comprises a clinical-histologic spectrum including fatty liver, alcoholic hepatitis (AH), and cirrhosis with its complications. Most patients are …		 Ashwani K Singal; Ramon Bataller; Joseph Ahn; Patrick S Kamath; Vijay H Shah;
2018 2 Inflammatory Bowel Disease
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2018 3 Complications Of Antireflux Surgery
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Abstract: Antireflux surgery anatomically restores the antireflux barrier and is a therapeutic option for proton pump inhibitor (PPI)-refractory gastroesophageal reflux disease or PPI …		 Rena Yadlapati; Eric S Hungness; John E Pandolfino;
2018 4 NASH Leading Cause Of Liver Transplant In Women: Updated Analysis Of Indications For Liver Transplant And Ethnic And Gender Variances
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Abstract: Chronic infection with hepatitis C virus (HCV) was previously the leading indication for liver transplant (LT) in the United States. However, since 2014 the use of direct-acting …		 MAZEN NOUREDDIN et. al.
2018 5 ACG Clinical Guideline: Diagnosis And Management Of Pancreatic Cysts
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Abstract: Pancreatic cysts are very common with the majority incidentally identified. There are several types of pancreatic cysts; some types can contain cancer or have malignant potential, …		 Grace H Elta; Brintha K Enestvedt; Bryan G Sauer; Anne Marie Lennon;
2018 6 Effect Of Antidepressants And Psychological Therapies In Irritable Bowel Syndrome: An Updated Systematic Review And Meta-Analysis
IF:3   Related Papers   Related Patents   Related Grants   Related Orgs   Related Experts   Details
Abstract: Irritable bowel syndrome (IBS) is a chronic functional bowel disorder that is thought to be due to a disorder of brain-gut function. Drugs acting centrally, such as …		 Alexander C Ford; Brian E Lacy; Lucinda A Harris; Eamonn M M Quigley; Paul Moayyedi;
2018 7 Primary Intestinal Lymphangiectasia (Waldmann’s Disease)
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 Arturo Borzutzky; Alberto Espino; Gigliola Alberti; Javiera Torres; Paul R Harris;
2018 8 Population Density And Risk Of Inflammatory Bowel Disease: A Prospective Population-Based Study In 13 Countries Or Regions In Asia-Pacific
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Abstract: Living in an urban environment may increase the risk of developing inflammatory bowel disease (IBD). It is unclear if this observation is seen globally. We conducted a …		 SIEW C NG et. al.
2018 9 Proton Pump Inhibitor Initiation And Withdrawal Affects Gut Microbiota And Readmission Risk In Cirrhosis
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Abstract: Cirrhosis is associated with gut microbial dysbiosis, high readmissions and proton pump inhibitor (PPI) overuse, which could be inter-linked. Our aim was to determine the effect …		 JASMOHAN S BAJAJ et. al.
2018 10 Efficacy And Tolerability Of Guanylate Cyclase-C Agonists For Irritable Bowel Syndrome With Constipation And Chronic Idiopathic Constipation: A Systematic Review And Meta-Analysis
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Abstract: Linaclotide and plecanatide are guanylate cyclase-C (GCC) agonists for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation …		 Eric D Shah; Hyungjin Myra Kim; Philip Schoenfeld;
2017 1 ACG Clinical Guideline: Treatment Of Helicobacter Pylori Infection
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Abstract: Helicobacter pylori (H. pylori) infection is a common worldwide infection that is an important cause of peptic ulcer disease and gastric cancer. H. pylori may also have a role in …		 William D Chey; Grigorios I Leontiadis; Colin W Howden; Steven F Moss;
2017 2 Colorectal Cancer Screening: Recommendations For Physicians And Patients From The U.S. Multi-Society Task Force On Colorectal Cancer
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Abstract: This document updates the colorectal cancer (CRC) screening recommendations of the U.S. Multi-Society Task Force of Colorectal Cancer (MSTF), which represents the American College …		 DOUGLAS K REX et. al.
2017 3 Hydrogen And Methane-Based Breath Testing In Gastrointestinal Disorders: The North American Consensus
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Abstract: Breath tests (BTs) are important for the diagnosis of carbohydrate maldigestion syndromes and small intestinal bacterial overgrowth (SIBO). However, standardization is lacking …		 ALI REZAIE et. al.
2017 4 ACG And CAG Clinical Guideline: Management Of Dyspepsia
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Abstract: We have updated both the American College of Gastroenterology (ACG) and the Canadian Association of Gastroenterology (CAG) guidelines on dyspepsia in a joint ACG/CAG dyspepsia …		 PAUL MOAYYEDI et. al.
2017 5 ACG Clinical Guideline: Preventive Care In Inflammatory Bowel Disease
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Abstract: Recent data suggest that inflammatory bowel disease (IBD) patients do not receive preventive services at the same rate as general medical patients. Patients with IBD often …		 Francis A Farraye; Gil Y Melmed; Gary R Lichtenstein; Sunanda V Kane;
2017 6 Inflammatory Bowel Disease
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2017 7 Trends In Epidemiology Of Pediatric Inflammatory Bowel Disease In Canada: Distributed Network Analysis Of Multiple Population-Based Provincial Health Administrative Databases
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Abstract: The incidence of pediatric-onset inflammatory bowel disease (IBD) is increasing worldwide. We used population-based health administrative data to determine national Canadian IBD …		 ERIC I BENCHIMOL et. al.
2017 8 Predicting The Future Burden Of Esophageal Cancer By Histological Subtype: International Trends In Incidence Up To 2030
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Abstract: Rapid increases in the incidence of esophageal adenocarcinoma (EAC) in high-income countries in the past decades have raised public health concerns. This study is the first to …		 Melina Arnold; Mathieu Laversanne; Linda Morris Brown; Susan S Devesa; Freddie Bray;
2017 9 Chronic Pancreatitis And Pancreatic Cancer Risk: A Systematic Review And Meta-analysis
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Abstract: Chronic pancreatitis is a putative risk factor for pancreatic cancer. The aim of this study was to examine the magnitude and temporality of this association. We searched MEDLINE …		 Jakob Kirkegård; Frank Viborg Mortensen; Deirdre Cronin-Fenton;
2017 10 Prevalence Of Nonalcoholic Steatohepatitis-Associated Cirrhosis In The United States: An Analysis Of National Health And Nutrition Examination Survey Data
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Abstract: Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of manifestations ranging from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH), fibrosis …		 MOHAMMAD NASSER KABBANY et. al.
2016 1 ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries
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Abstract: Clinicians are required to assess abnormal liver chemistries on a daily basis. The most common liver chemistries ordered are serum alanine aminotransferase (ALT), aspartate …		 Paul Y Kwo; Stanley M Cohen; Joseph K Lim;
2016 2 Age As A Confounding Factor For The Accurate Non-Invasive Diagnosis Of Advanced NAFLD Fibrosis
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Abstract: Non-invasive fibrosis scores are widely used to identify/exclude advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). However, these scores were …		 STUART MCPHERSON et. al.
2016 3 A Randomized Controlled Trial Comparing The Low FODMAP Diet Vs. Modified NICE Guidelines In US Adults With IBS-D
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Abstract: There has been an increasing interest in the role of fermentable oligo-, di-, and monosaccharides and polyols (FODMAPs) in irritable bowel syndrome (IBS). We report results from …		 Shanti L Eswaran; William D Chey; Theresa Han-Markey; Sarah Ball; Kenya Jackson;
2016 4 ACG Clinical Guideline: Management Of Patients With Acute Lower Gastrointestinal Bleeding
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 Lisa L Strate; Ian M Gralnek;
2016 5 Inflammatory Bowel Disease
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2016 6 ACG Clinical Guideline: Diagnosis, Treatment, And Prevention Of Acute Diarrheal Infections In Adults
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Abstract: Acute diarrheal infections are a common health problem globally and among both individuals in the United States and traveling to developing world countries. Multiple modalities …		 Mark S Riddle; Herbert L DuPont; Bradley A Connor;
2016 7 Recommendations On Fecal Immunochemical Testing To Screen For Colorectal Neoplasia: A Consensus Statement By The US Multi-Society Task Force On Colorectal Cancer
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Abstract: The use of the fecal occult blood test (FOBT) for colorectal cancer (CRC) screening is supported by randomized trials demonstrating effectiveness in cancer prevention and widely …		 DOUGLAS J ROBERTSON et. al.
2016 8 Post-Colonoscopy Complications: A Systematic Review, Time Trends, And Meta-Analysis Of Population-Based Studies
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Abstract: Many studies around the world addressed the post-colonoscopy complications, but their pooled prevalence and time trends are unknown. We performed a systematic review and …		 ANKIE REUMKENS et. al.
2016 9 Association Of Vitamin D Level With Clinical Status In Inflammatory Bowel Disease: A 5-Year Longitudinal Study
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Abstract: Emerging data suggest that vitamin D has a significant role in inflammatory bowel disease (IBD). Prospective data evaluating the association of vitamin D serum status and disease …		 TOUFIC A KABBANI et. al.
2016 10 ACG Clinical Guideline: Liver Disease And Pregnancy
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Abstract: Consultation for liver disease in pregnant women is a common and oftentimes vexing clinical consultation for the gastroenterologist. The challenge lies in the need to consider the …		 Tram T Tran; Joseph Ahn; Nancy S Reau;
2015 1 Selecting Therapeutic Targets In Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals For Treat-to-Target
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Abstract: The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) program was initiated by the International Organization for the Study of Inflammatory Bowel Diseases …		 L PEYRIN-BIROULET et. al.
2015 2 ACG Clinical Guideline: Genetic Testing And Management Of Hereditary Gastrointestinal Cancer Syndromes
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Abstract: This guideline presents recommendations for the management of patients with hereditary gastrointestinal cancer syndromes. The initial assessment is the collection of a family …		 SAPNA SYNGAL et. al.
2015 3 ACG Clinical Guideline: Diagnosis And Management Of Small Bowel Bleeding
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Abstract: Bleeding from the small intestine remains a relatively uncommon event, accounting for ~5-10% of all patients presenting with gastrointestinal (GI) bleeding. Given advances in …		 Lauren B Gerson; Jeff L Fidler; David R Cave; Jonathan A Leighton;
2015 4 C-Reactive Protein, Fecal Calprotectin, And Stool Lactoferrin For Detection Of Endoscopic Activity In Symptomatic Inflammatory Bowel Disease Patients: A Systematic Review And Meta-Analysis
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Abstract: Persistent disease activity is associated with a poor prognosis in inflammatory bowel disease (IBD). Therefore, monitoring of patients with intent to suppress subclinical …		 MAHMOUD H MOSLI et. al.
2015 5 ACG Clinical Guideline: Primary Sclerosing Cholangitis
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Abstract: Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly …		 Keith D Lindor; Kris V Kowdley; M Edwyn Harrison; ME;
2015 6 Intestinal Microbiota And Diet In IBS: Causes, Consequences, Or Epiphenomena?
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Abstract: Irritable bowel syndrome (IBS) is a heterogeneous functional disorder with a multifactorial etiology that involves the interplay of both host and environmental factors. Among …		 MIRJANA RAJILIĆ-STOJANOVIĆ et. al.
2015 7 A Meta-analysis Of The Utility Of C-reactive Protein, Erythrocyte Sedimentation Rate, Fecal Calprotectin, And Fecal Lactoferrin To Exclude Inflammatory Bowel Disease In Adults With IBS
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Abstract: Irritable bowel syndrome (IBS) is viewed as a diagnosis of exclusion by most providers. The aim of our study was to perform a systematic review and meta-analysis to evaluate the …		 Stacy B Menees; Corey Powell; Jacob Kurlander; Akash Goel; William D Chey;
2015 8 Local Recurrence After Endoscopic Resection For Large Colorectal Neoplasia: A Multicenter Prospective Study In Japan
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Abstract: Conventional endoscopic resection (CER) is a widely accepted treatment for early colorectal neoplasia; however, large colorectal neoplasias remain problematic, as they necessitate …		 SHIRO OKA et. al.
2015 9 Inflammatory Bowel Disease
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2015 10 Forty-Year Analysis Of Colonoscopic Surveillance Program For Neoplasia In Ulcerative Colitis: An Updated Overview
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Abstract: This study provides an overview of the largest and longest-running colonoscopic surveillance program for colorectal cancer (CRC) in patients with long-standing ulcerative colitis …		 CHANG-HO RYAN CHOI et. al.
2014 1 Quality Indicators For Colonoscopy
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 DOUGLAS K REX et. al.
2014 2 Fecal Microbiota Transplant For Treatment Of Clostridium Difficile Infection In Immunocompromised Patients
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Abstract: Patients who are immunocompromised (IC) are at increased risk of Clostridium difficile infection (CDI), which has increased to epidemic proportions over the past decade. Fecal …		 COLLEEN R KELLY et. al.
2014 3 Efficacy Of Prebiotics, Probiotics, And Synbiotics In Irritable Bowel Syndrome And Chronic Idiopathic Constipation: Systematic Review And Meta-analysis
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Abstract: Irritable bowel syndrome (IBS) and chronic idiopathic constipation (CIC) are functional bowel disorders. Evidence suggests that disturbance in the gastrointestinal microbiota may …		 ALEXANDER C FORD et. al.
2014 4 American College Of Gastroenterology Monograph On The Management Of Irritable Bowel Syndrome And Chronic Idiopathic Constipation
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 ALEXANDER C FORD et. al.
2014 5 ACG Clinical Guideline: The Diagnosis And Management Of Idiosyncratic Drug-induced Liver Injury
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Abstract: Idiosyncratic drug-induced liver injury (DILI) is a rare adverse drug reaction and it can lead to jaundice, liver failure, or even death. Antimicrobials and herbal and dietary …		 NAGA P CHALASANI et. al.
2014 6 Effect Of Antidepressants And Psychological Therapies, Including Hypnotherapy, In Irritable Bowel Syndrome: Systematic Review And Meta-analysis
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Abstract: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder. Evidence relating to the treatment of this condition with antidepressants and psychological …		 ALEXANDER C FORD et. al.
2014 7 Guidelines On Genetic Evaluation And Management Of Lynch Syndrome: A Consensus Statement By The US Multi-society Task Force On Colorectal Cancer
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Abstract: The Multi-Society Task Force, in collaboration with invited experts, developed guidelines to assist health care providers with the appropriate provision of genetic testing and …		 FRANCIS M GIARDIELLO et. al.
2014 8 Changing Hepatocellular Carcinoma Incidence And Liver Cancer Mortality Rates In The United States
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Abstract: The objectives were to describe Surveillance, Epidemiology and End Results (SEER) hepatocellular carcinoma (HCC) incidence trends and the US liver cancer mortality trends by …		 Sean F Altekruse; S Jane Henley; James E Cucinelli; Katherine A McGlynn;
2014 9 The Effect Of Fiber Supplementation On Irritable Bowel Syndrome: A Systematic Review And Meta-analysis
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Abstract: Fiber has been used for many years to treat irritable bowel syndrome (IBS). This approach had fallen out of favor until a recent resurgence, which was based on new randomized …		 PAUL MOAYYEDI et. al.
2014 10 The Effect Of PNPLA3 On Fibrosis Progression And Development Of Hepatocellular Carcinoma: A Meta-analysis
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Abstract: The PNPLA3 rs738409 single-nucleotide polymorphism is known to promote nonalcoholic steatohepatitis (NASH), but its association with fibrosis severity and hepatocellular carcinoma …		 AMIT G SINGAL et. al.
2013 1 Guidelines For Diagnosis, Treatment, And Prevention Of Clostridium Difficile Infections
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Abstract: Clostridium difficile infection (CDI) is a leading cause of hospital-associated gastrointestinal illness and places a high burden on our health-care system. Patients with CDI …		 CHRISTINA M SURAWICZ et. al.
2013 2 American College Of Gastroenterology Guideline: Management Of Acute Pancreatitis
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Abstract: This guideline presents recommendations for the management of patients with acute pancreatitis (AP). During the past decade, there have been new understandings and developments in …		 Scott Tenner; John Baillie; John DeWitt; Santhi Swaroop Vege; SS;
2013 3 Guidelines For The Diagnosis And Management Of Gastroesophageal Reflux Disease
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 Philip O Katz; Lauren B Gerson; Marcelo F Vela;
2013 4 ACG Clinical Guidelines: Diagnosis And Management Of Celiac Disease
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Abstract: This guideline presents recommendations for the diagnosis and management of patients with celiac disease. Celiac disease is an immune-based reaction to dietary gluten (storage …		 ALBERTO RUBIO-TAPIA et. al.
2013 5 ACG Clinical Guideline: Evidenced Based Approach To The Diagnosis And Management Of Esophageal Eosinophilia And Eosinophilic Esophagitis (EoE)
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Abstract: Esophageal eosinophilia and eosinophilic esophagitis (EoE) are increasingly recognized and prevalent conditions, which now represent common clinical problems encountered by …		 EVAN S DELLON et. al.
2013 6 Fecal Microbiota Transplantation For Clostridium Difficile Infection: Systematic Review And Meta-analysis
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Abstract: The clinical and economic burden of Clostridium difficile infection (CDI) is significant. Recurrent CDI management has emerged as a major challenge with suboptimal response to …		 Zain Kassam; Christine H Lee; Yuhong Yuan; Richard H Hunt;
2013 7 ACG Clinical Guideline: Diagnosis And Management Of Achalasia
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Abstract: Achalasia is a primary motor disorder of the esophagus characterized by insufficient lower esophageal sphincter relaxation and loss of esophageal peristalsis. This results in …		 Michael F Vaezi; John E Pandolfino; Marcelo F Vela;
2013 8 Population-attributable Fractions Of Risk Factors For Hepatocellular Carcinoma In The United States
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Abstract: Risk factors for hepatocellular carcinoma (HCC) include hepatitis B and C viruses (HBV, HCV), excessive alcohol consumption, rare genetic disorders and diabetes/obesity. The …		 TANIA M WELZEL et. al.
2013 9 Temporal Bacterial Community Dynamics Vary Among Ulcerative Colitis Patients After Fecal Microbiota Transplantation
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Abstract: Fecal microbiota transplantation (FMT) from healthy donors, which is an effective alternative for treatment of Clostridium difficile-associated disease, is being considered for …		 SIEGLINDE ANGELBERGER et. al.
2013 10 Self-reported Food-related Gastrointestinal Symptoms In IBS Are Common And Associated With More Severe Symptoms And Reduced Quality Of Life
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Abstract: Despite the fact that food and diet are central issues, that concern patients with irritable bowel syndrome (IBS), the current understanding about the association between the …		 Lena Böhn; Stine Störsrud; Hans Törnblom; Ulf Bengtsson; Magnus Simrén;
2012 1 The Diagnosis And Management Of Non-alcoholic Fatty Liver Disease: Practice Guideline By The American Association For The Study Of Liver Diseases, American College Of Gastroenterology, And The American Gastroenterological Association
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 NAGA CHALASANI et. al.
2012 2 Serrated Lesions Of The Colorectum: Review And Recommendations From An Expert Panel
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Abstract: Serrated lesions of the colorectum are the precursors of perhaps one-third of colorectal cancers (CRCs). Cancers arising in serrated lesions are usually in the proximal colon, and …		 DOUGLAS K REX et. al.
2012 3 Clinical Guideline: Management Of Gastroparesis
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Abstract: This guideline presents recommendations for the evaluation and management of patients with gastroparesis. Gastroparesis is identified in clinical practice through the recognition …		 MICHAEL CAMILLERI et. al.
2012 4 Standardized Frozen Preparation For Transplantation Of Fecal Microbiota For Recurrent Clostridium Difficile Infection
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Abstract: While fecal microbiota transplantation (FMT) is historically known to be an effective means to treat recurrent Clostridium difficile infection (CDI) refractory to standard …		 Matthew J Hamilton; Alexa R Weingarden; Michael J Sadowsky; Alexander Khoruts;
2012 5 Long-term Follow-up Of Colonoscopic Fecal Microbiota Transplant For Recurrent Clostridium Difficile Infection
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Abstract: Clostridium difficile infection (CDI) has increased to epidemic proportions over the past 15 years, and recurrence rates of 30-65% with failure to respond to multiple courses of …		 LAWRENCE J BRANDT et. al.
2012 6 The Prevalence Of Celiac Disease In The United States
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Abstract: The prevalence of celiac disease (CD) in the United States is unknown. We sought to estimate CD prevalence nationwide by using a nationally representative sample. This study …		 Alberto Rubio-Tapia; Jonas F Ludvigsson; Tricia L Brantner; Joseph A Murray; James E Everhart;
2012 7 Management Of Patients With Ulcer Bleeding
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Abstract: This guideline presents recommendations for the step-wise management of patients with overt upper gastrointestinal bleeding. Hemodynamic status is first assessed, and …		 Loren Laine; Dennis M Jensen;
2012 8 Risk Of Clostridium Difficile Infection With Acid Suppressing Drugs And Antibiotics: Meta-analysis
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Abstract: Several studies have raised concern regarding the possible association between proton-pump inhibitors (PPIs) and Clostridium difficile infection (CDI). We aimed to perform a …		 CHUN SHING KWOK et. al.
2012 9 Clostridium Difficile-associated Diarrhea And Proton Pump Inhibitor Therapy: A Meta-analysis
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Abstract: Clostridium difficile-associated diarrhea (CDAD) is a major cause of morbidity and increasing health-care costs among hospitalized patients. Although exposure to antibiotics …		 Sailajah Janarthanan; Ivo Ditah; Douglas G Adler; Murray N Ehrinpreis;
2012 10 Prevalence Of Symptoms Meeting Criteria For Irritable Bowel Syndrome In Inflammatory Bowel Disease: Systematic Review And Meta-analysis
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Abstract: Symptoms compatible with irritable bowel syndrome (IBS) may co-exist in patients with inflammatory bowel disease (IBD), presenting a clinical dilemma for physicians. We conducted …		 Stephen J Halpin; Alexander C Ford;
2011 1 Dietary Intake And Risk Of Developing Inflammatory Bowel Disease: A Systematic Review Of The Literature
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Abstract: The incidence of inflammatory bowel disease (IBD) is increasing. Dietary factors such as the spread of the Western diet, high in fat and protein but low in fruits and …		 Jason K Hou; Bincy Abraham; Hashem El-Serag;
2011 2 The Epidemiology Of Community-acquired Clostridium Difficile Infection: A Population-based Study
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Abstract: Clostridium difficile infection (CDI) is a common hospital-acquired infection with increasing incidence, severity, recurrence, and associated morbidity and mortality. There are …		 SAHIL KHANNA et. al.
2011 3 Efficacy Of Biological Therapies In Inflammatory Bowel Disease: Systematic Review And Meta-analysis
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Abstract: Crohn’s disease (CD) and ulcerative colitis (UC) are inflammatory disorders of the gastrointestinal tract of unknown etiology. Evidence for treatment of the condition with …		 ALEXANDER C FORD et. al.
2011 4 Radiofrequency Ablation For Hepatocellular Carcinoma: 10-year Outcome And Prognostic Factors
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Abstract: Radiofrequency ablation (RFA) is widely performed for hepatocellular carcinoma (HCC). However, there has been no report on 10-year outcome of RFA. The objective of this study was …		 SHUICHIRO SHIINA et. al.
2011 5 Gluten Causes Gastrointestinal Symptoms In Subjects Without Celiac Disease: A Double-blind Randomized Placebo-controlled Trial
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Abstract: Despite increased prescription of a gluten-free diet for gastrointestinal symptoms in individuals who do not have celiac disease, there is minimal evidence that suggests that …		 JESSICA R BIESIEKIERSKI et. al.
2011 6 Prevalence Of, And Risk Factors For, Chronic Idiopathic Constipation In The Community: Systematic Review And Meta-analysis
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Abstract: Chronic idiopathic constipation (CIC) is a common functional gastrointestinal disorder in the community, yet no previous systematic review and meta-analysis has estimated the …		 Nicole C Suares; Alexander C Ford;
2011 7 Antibiotic Therapy In Inflammatory Bowel Disease: A Systematic Review And Meta-analysis
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Abstract: The etiology of inflammatory bowel disease (IBD) is unknown but may relate to an unidentified bacterial pathogen or an immunological reaction to gut microbiota. Antibiotics have …		 KHURRAM J KHAN et. al.
2011 8 Peroral Endoscopic Myotomy For The Treatment Of Achalasia: A Prospective Single Center Study
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Abstract: Endoscopic balloon dilatation and laparoscopic myotomy are established treatments for achalasia. Recently, a new endoscopic technique for complete myotomy was described. Herein, …		 DANIEL VON RENTELN et. al.
2011 9 Loss Of Response And Need For Adalimumab Dose Intensification In Crohn’s Disease: A Systematic Review
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Abstract: The objective of this study was to review loss of response and need for adalimumab dose intensification in adult and pediatric patients with Crohn’s disease. Studies were …		 Vincent Billioud; William J Sandborn; Laurent Peyrin-Biroulet;
2011 10 Hospital Readmissions Among Patients With Decompensated Cirrhosis
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Abstract: Early rehospitalizations have been well characterized in many disease states, but not among patients with cirrhosis. The aims of this study were to identify the frequency, costs, …		 Michael L Volk; Rachel S Tocco; Jessica Bazick; Mina O Rakoski; Anna S Lok;
2010 1 Ulcerative Colitis Practice Guidelines In Adults: American College Of Gastroenterology, Practice Parameters Committee
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Abstract: Guidelines for clinical practice are aimed to indicate preferred approaches to medical problems as established by scientifically valid research. Double-blind placebo controlled …		 Asher Kornbluth; David B Sachar; DB;
2010 2 Mucolytic Bacteria With Increased Prevalence In IBD Mucosa Augment In Vitro Utilization Of Mucin By Other Bacteria
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Abstract: Mucosa-associated bacteria are increased in inflammatory bowel disease (IBD), which suggests the possibility of an increased source of digestible endogenous mucus substrate. We …		 CHIN WEN PNG et. al.
2010 3 The Natural History of Adult Crohn’s Disease in Population-Based Cohorts
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Abstract: OBJECTIVES:Natural history studies provide invaluable data on the disease course. First, they help define the end points for clinical trials that are designed to test drugs for …		 Laurent Peyrin-Biroulet; Edward V Loftus; Jean-Frederic Colombel; William J Sandborn;
2010 4 Clinical Utility Of Measuring Infliximab And Human Anti-chimeric Antibody Concentrations In Patients With Inflammatory Bowel Disease
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Abstract: Human anti-chimeric antibodies (HACAs) and subtherapeutic infliximab concentrations are associated with decreased duration of response. We evaluated the clinical utility of …		 WAQQAS AFIF et. al.
2010 5 Fecal Calprotectin Correlates More Closely With The Simple Endoscopic Score for Crohn’s Disease (SES-CD) Than CRP, Blood Leukocytes, and The CDAI
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Abstract: OBJECTIVES:Studies evaluating the correlation between the widely used Simple Endoscopic Score for Crohn’s disease (SES-CD) and noninvasive markers are scarce. The aim of this …		 ALAIN M SCHOEPFER et. al.
2010 6 ACCF/ACG/AHA 2010 Expert Consensus Document On The Concomitant Use Of Proton Pump Inhibitors And Thienopyridines: A Focused Update Of The ACCF/ACG/AHA 2008 Expert Consensus Document On Reducing The Gastrointestinal Risks Of Antiplatelet Therapy And NSAID Use
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 NEENA S ABRAHAM et. al.
2010 7 Prevalence Of Incidental Pancreatic Cysts In The Adult Population On MR Imaging
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Abstract: The reporting of incidental pancreatic cystic lesions on cross-sectional imaging studies has dramatically increased over the last few years. The prevalence of incidental …		 Karen S Lee; Aarti Sekhar; Neil M Rofsky; Ivan Pedrosa;
2010 8 The London Position Statement Of The World Congress Of Gastroenterology On Biological Therapy For IBD With The European Crohn’s And Colitis Organization: When To Start, When To Stop, Which Drug To Choose, And How To Predict Response?
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Abstract: The advent of biological therapy has revolutionized inflammatory bowel disease (IBD) care. Nonetheless, not all patients require biological therapy. Selection of patients depends …		 GEERT R D’HAENS et. al.
2010 9 Gastroduodenal Disorders
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 Jan Tack; Nicholas J Talley;
2010 10 Low-grade Dysplasia In Barrett’s Esophagus: Overdiagnosed And Underestimated
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Abstract: Published data on the natural history of low-grade dysplasia (LGD) in Barrett’s esophagus (BE) are inconsistent and difficult to interpret. We investigated the natural history of …		 WOUTER L CURVERS et. al.