Most Influential JOURNAL OF THE NATIONAL CANCER INSTITUTE Papers
The Journal of the National Cancer Institute publishes peer-reviewed original research from around the world and is internationally acclaimed as the source for the most up-to-date information from the rapidly changing fields of cancer research and treatment. Paper Digest Team analyze all papers published on JOURNAL OF THE NATIONAL CANCER INSTITUTE in the past years, and presents the 10 most influential papers for each year (based on when the paper became available online). This ranking list is automatically constructed based upon citations from both research papers and granted patents, and will be frequently updated to reflect the most recent changes. To find the most influential papers from other conferences/journals, visit Best Paper Digest page. Note: the most influential papers may or may not include the papers that won the best paper awards. (Last updated on: 2021-05-23)
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TABLE 1: Most Influential JOURNAL OF THE NATIONAL CANCER INSTITUTE Papers
| Year | Rank | Paper | Author(s) |
|---|---|---|---|
| 2020 | 1 | Clinical Characteristics and Outcomes of COVID-19-Infected Cancer Patients: A Systematic Review and Meta-Analysis IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Previous studies have indicated coronavirus disease 2019 (COVID-19) patients with cancer have a high fatality rate. We conducted a systematic review of studies that reported … |
HUA ZHANG et. al. |
| 2020 | 2 | The Contribution of Germline Predisposition Gene Mutations to Clinical Subtypes of Invasive Breast Cancer From A Clinical Genetic Testing Cohort IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The germline cancer predisposition genes associated with increased risk of each clinical subtype of breast cancer, defined by estrogen receptor (ER), progesterone receptor (PR), … |
CHUNLING HU et. al. |
| 2020 | 3 | Effect of Aspirin on Cancer Incidence and Mortality in Older Adults IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: ASPirin in Reducing Events in the Elderly, a randomized, double-blind, placebo-controlled trial of daily low-dose aspirin (100 mg) in older adults, showed an increase in all-cause … |
JOHN J MCNEIL et. al. |
| 2020 | 4 | Predicting The Pathologic Complete Response After Neoadjuvant Pembrolizumab in Muscle-Invasive Bladder Cancer IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: In the PURE-01 study (NCT02736266), we aimed to evaluate the ability to predict the pathologic complete response (pT0N0) after pembrolizumab by using clinical and tumor … |
MARCO BANDINI et. al. |
| 2020 | 5 | Management of Cancer and Health After The Clinic Visit: A Call to Action for Self-Management in Cancer Care IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Individuals with cancer and their families assume responsibility for management of cancer as an acute and chronic disease. Yet, cancer lags other chronic diseases in its provision … |
DORIS HOWELL et. al. |
| 2020 | 6 | Prevalence And Outcome Of COVID-19 Infection In Cancer Patients: A National Veterans Affairs Study IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Emerging data suggest variability in susceptibility and outcome to COVID-19 infection. Identifying risk-factors associated with infection and outcomes in cancer patients is … |
NATHANAEL R FILLMORE et. al. |
| 2020 | 7 | BRCA1 Promoter Methylation and Clinical Outcomes in Ovarian Cancer: An Individual Patient Data Meta-Analysis IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: BRCA1 methylation has been associated with homologous recombination deficiency, a biomarker of platinum sensitivity. Studies evaluating BRCA1-methylated tubal and ovarian cancer … |
ROSHNI D KALACHAND et. al. |
| 2020 | 8 | Weathering The Storm: Managing Older Adults With Breast Cancer Amid COVID-19 and Beyond IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Caring for older patients with breast cancer presents unique clinical considerations because of preexisting and competing comorbidity, the potential for treatment-related … |
RACHEL A FREEDMAN et. al. |
| 2020 | 9 | Sex and Adverse Events of Adjuvant Chemotherapy in Colon Cancer: An Analysis of 34 640 Patients in The ACCENT Database IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Adjuvant chemotherapy is a standard treatment option for patients with stage III and high-risk stage II colon cancer. Sex is one of several factors responsible for the wide … |
ANNA D WAGNER et. al. |
| 2020 | 10 | Race, Ethnicity, and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer in The Randomized TAILORx Trial IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Black race is associated with worse outcomes in early breast cancer. We evaluated clinicopathologic characteristics, the 21-gene recurrence score (RS), treatment delivered, and … |
KATHY S ALBAIN et. al. |
| 2019 | 1 | Recent Trends in Squamous Cell Carcinoma of The Anus Incidence and Mortality in The United States, 2001-2015 IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Squamous cell carcinoma of the anus (SCCA) incidence is rising in the United States. Study of incidence trends by stage at diagnosis, age-specific and birth cohort patterns, and … |
ASHISH A DESHMUKH et. al. |
| 2019 | 2 | Response IF:2 Related Papers Related Patents Related Grants Related Orgs Related Experts Details |
JOHANNA M MEULEPAS et. al. |
| 2019 | 3 | Efficacy, Safety, And Immunogenicity Of An Escherichia Coli-Produced Bivalent Human Papillomavirus Vaccine: An Interim Analysis Of A Randomized Clinical Trial IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The high cost and insufficient supply of human papillomavirus (HPV) vaccines have slowed the pace of controlling cervical cancer. A phase III clinical trial was conducted to … |
YOU-LIN QIAO et. al. |
| 2019 | 4 | Radiomics Response Signature for Identification of Metastatic Colorectal Cancer Sensitive to Therapies Targeting EGFR Pathway IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The authors sought to forecast survival and enhance treatment decisions for patients with liver metastatic colorectal cancer by using on-treatment radiomics signature to predict … |
LAURENT DERCLE et. al. |
| 2019 | 5 | Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The purpose of this study was to estimate precise age-specific tubo-ovarian carcinoma (TOC) and breast cancer (BC) risks for carriers of pathogenic variants in RAD51C and RAD51D. … |
XIN YANG et. al. |
| 2019 | 6 | The Molecular Analysis for Therapy Choice (NCI-MATCH) Trial: Lessons for Genomic Trial Design IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The proportion of tumors of various histologies that may respond to drugs targeted to molecular alterations is unknown. NCI-MATCH, a collaboration between ECOG-ACRIN Cancer … |
KEITH T FLAHERTY et. al. |
| 2019 | 7 | A Comparative Modeling Analysis of Risk-Based Lung Cancer Screening Strategies IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Risk-prediction models have been proposed to select individuals for lung cancer screening. However, their long-term effects are uncertain. This study evaluates long-term benefits … |
KEVIN TEN HAAF et. al. |
| 2019 | 8 | Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Observational data have shown that some cancer survivors develop chronic conditions like frailty, sarcopenia, cardiac dysfunction, and mild cognitive impairment earlier and/or at … |
JENNIFER L GUIDA et. al. |
| 2019 | 9 | Immune Checkpoint Profiles in Luminal B Breast Cancer (Alliance) IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Unlike estrogen receptor (ER)-negative breast cancer, ER-positive breast cancer outcome is less influenced by lymphocyte content, indicating the presence of immune tolerance … |
MEENAKSHI ANURAG et. al. |
| 2019 | 10 | Addition Of Platinum Derivatives To Fluoropyrimidine-Based Neoadjuvant Chemoradiotherapy For Stage II/III Rectal Cancer: Systematic Review And Meta-Analysis IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Current guidelines recommend neoadjuvant therapy for patients with stage II or III rectal cancer. The addition of platinum derivatives to fluoropyrimidine-based chemoradiotherapy … |
FELIX J HÜTTNER et. al. |
| 2018 | 1 | Triple-Negative Breast Cancer Risk Genes Identified By Multigene Hereditary Cancer Panel Testing IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Germline genetic testing with hereditary cancer gene panels can identify women at increased risk of breast cancer. However, those at increased risk of triple-negative (estrogen … |
HERMELA SHIMELIS et. al. |
| 2018 | 2 | Stand-Alone Artificial Intelligence For Breast Cancer Detection In Mammography: Comparison With 101 Radiologists IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Artificial intelligence (AI) systems performing at radiologist-like levels in the evaluation of digital mammography (DM) would improve breast cancer screening accuracy and … |
ALEJANDRO RODRIGUEZ-RUIZ et. al. |
| 2018 | 3 | An Observational Study Of Deep Learning And Automated Evaluation Of Cervical Images For Cancer Screening IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Human papillomavirus vaccination and cervical screening are lacking in most lower resource settings, where approximately 80% of more than 500 000 cancer cases occur annually. … |
LIMING HU et. al. |
| 2018 | 4 | Biomarkers For Homologous Recombination Deficiency In Cancer IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Defective DNA repair is a common hallmark of cancer. Homologous recombination is a DNA repair pathway of clinical interest due to the sensitivity of homologous … |
Michal M Hoppe; Raghav Sundar; David S P Tan; Anand D Jeyasekharan; |
| 2018 | 5 | Comprehensive Study of The Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The BRCA1-associated protein-1 (BAP1) tumor predisposition syndrome (BAP1-TPDS) is a hereditary tumor syndrome caused by germline pathogenic variants in BAP1 encoding a tumor … |
SEBASTIAN WALPOLE et. al. |
| 2018 | 6 | Radiation Exposure From Pediatric CT Scans And Subsequent Cancer Risk In The Netherlands IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Computed tomography (CT), a strong diagnostic tool, delivers higher radiation doses than most imaging modalities. As CT use has increased rapidly, radiation protection is … |
JOHANNA M MEULEPAS et. al. |
| 2018 | 7 | Antibody-Drug Conjugate-Based Therapeutics: State Of The Science IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Antibody-drug conjugates (ADCs) are complex engineered therapeutics consisting of monoclonal antibodies, directed toward tumor-associated antigens, to which highly potent … |
Michael J Birrer; Kathleen N Moore; Ilaria Betella; Richard C Bates; |
| 2018 | 8 | Systematic Review And Meta-Analysis Of The Magnitude Of Structural, Clinical, And Physician And Patient Barriers To Cancer Clinical Trial Participation IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Barriers to cancer clinical trial participation have been the subject of frequent study, but the rate of trial participation has not changed substantially over time. Studies often … |
Joseph M Unger; Riha Vaidya; Dawn L Hershman; Lori M Minasian; Mark E Fleury; |
| 2018 | 9 | The Immune Landscape Of Prostate Cancer And Nomination Of PD-L2 As A Potential Therapeutic Target IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Immunotherapy has been less successful in treating prostate cancer than other solid tumors. We sought to better understand the immune landscape in prostate cancer and identify … |
SHUANG G ZHAO et. al. |
| 2018 | 10 | Breast Cancer Screening Using Tomosynthesis Or Mammography: A Meta-analysis Of Cancer Detection And Recall IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Tomosynthesis approximates a 3D mammogram of the breast, reducing parenchymal overlap that masks cancers or creates false lesions on 2D mammography, and potentially enabling … |
M Luke Marinovich; Kylie E Hunter; Petra Macaskill; Nehmat Houssami; |
| 2017 | 1 | Novel Role Of FBXW7 Circular RNA In Repressing Glioma Tumorigenesis IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Circular RNAs (circRNAs) are RNA transcripts that are widespread in the eukaryotic genome. Recent evidence indicates that circRNAs play important roles in tissue development, gene … |
YIBING YANG et. al. |
| 2017 | 2 | International Patterns And Trends In Endometrial Cancer Incidence, 1978-2013 IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Cancers of the corpus uteri-primarily of the endometrium-rank as the sixth most common neoplasm in women worldwide. Analyses of the global patterns and trends of uterine cancer … |
Joannie Lortet-Tieulent; Jacques Ferlay; Freddie Bray; Ahmedin Jemal; |
| 2017 | 3 | Concordance Of Circulating Tumor DNA And Matched Metastatic Tissue Biopsy In Prostate Cancer IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Real-time knowledge of the somatic genome can influence management of patients with metastatic castration-resistant prostate cancer (mCRPC). While routine metastatic tissue biopsy … |
ALEXANDER W WYATT et. al. |
| 2017 | 4 | ALK, ROS1, And NTRK Rearrangements In Metastatic Colorectal Cancer IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: ALK, ROS1, and NTRK fusions occur in 0.2% to 2.4% of colorectal cancers. Pioneer cases of metastatic colorectal cancer (mCRC) patients bearing rearrangements who benefited from … |
FILIPPO PIETRANTONIO et. al. |
| 2017 | 5 | Real-world Data For Clinical Evidence Generation In Oncology IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Conventional cancer clinical trials can be slow and costly, often produce results with limited external validity, and are difficult for patients to participate in. Recent … |
Sean Khozin; Gideon M Blumenthal; Richard Pazdur; |
| 2017 | 6 | Prognostic Value of BRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Background The prognostic value of BRAF and KRAS mutations within microsatellite-unstable (MSI) and microsatellite-stable (MSS) subgroups of resected colon carcinoma patients … |
JULIEN TAIEB et. al. |
| 2017 | 7 | Circulating Tumor Cells in Breast Cancer Patients Treated By Neoadjuvant Chemotherapy: A Meta-analysis IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: We conducted a meta-analysis in nonmetastatic breast cancer patients treated by neoadjuvant chemotherapy (NCT) to assess the clinical validity of circulating tumor cell (CTC) … |
FRANÇOIS-CLÉMENT BIDARD et. al. |
| 2017 | 8 | Reporting Recommendations For Tumor Marker Prognostic Studies (REMARK): An Abridged Explanation And Elaboration IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK) were developed to address widespread deficiencies in the reporting of such studies. The REMARK checklist … |
Willi Sauerbrei; Sheila E Taube; Lisa M McShane; Margaret M Cavenagh; Douglas G Altman; |
| 2017 | 9 | Circulating Vitamin D And Colorectal Cancer Risk: An International Pooling Project Of 17 Cohorts IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Experimental and epidemiological studies suggest a protective role for vitamin D in colorectal carcinogenesis, but evidence is inconclusive. Circulating 25-hydroxyvitamin D … |
MARJORIE L MCCULLOUGH et. al. |
| 2017 | 10 | Advancing Symptom Science Through Symptom Cluster Research: Expert Panel Proceedings And Recommendations IF:3 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: An overview of proceedings, findings, and recommendations from the workshop on Advancing Symptom Science Through Symptom Cluster Research sponsored by the National Institute of … |
CHRISTINE MIASKOWSKI et. al. |
| 2016 | 1 | HPV Involvement In Head And Neck Cancers: Comprehensive Assessment Of Biomarkers In 3680 Patients IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: We conducted a large international study to estimate fractions of head and neck cancers (HNCs) attributable to human papillomavirus (HPV-AFs) using six HPV-related biomarkers of … |
XAVIER CASTELLSAGUÉ et. al. |
| 2016 | 2 | Long-term Outcome Of An Organ Preservation Program After Neoadjuvant Treatment For Rectal Cancer IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The aim of this study was to establish the oncological and functional results of organ preservation with a watch-and-wait approach (W&W) and selective transanal endoscopic … |
MILOU H MARTENS et. al. |
| 2016 | 3 | Chimeric Antigen Receptors Modified T-Cells For Cancer Therapy IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The genetic modification and characterization of T-cells with chimeric antigen receptors (CARs) allow functionally distinct T-cell subsets to recognize specific tumor cells. The … |
Hanren Dai; Yao Wang; Xuechun Lu; Weidong Han; |
| 2016 | 4 | Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Previously we identified a DNA damage response-deficient (DDRD) molecular subtype within breast cancer. A 44-gene assay identifying this subtype was validated as predicting … |
EILEEN E PARKES et. al. |
| 2016 | 5 | Financial Hardships Experienced By Cancer Survivors: A Systematic Review IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: With rising cancer care costs, including high-priced cancer drugs, financial hardship is increasingly documented among cancer survivors in the United States; research findings … |
Cheryl K Altice; Matthew P Banegas; Reginald D Tucker-Seeley; K Robin Yabroff; |
| 2016 | 6 | Comparison Of EndoPredict And EPclin With Oncotype DX Recurrence Score For Prediction Of Risk Of Distant Recurrence After Endocrine Therapy IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Estimating distant recurrence (DR) risk among women with estrogen receptor-positive (ER+), human epidermal growth factor receptor 2 (HER2)-negative early breast cancer helps … |
RICHARD BUUS et. al. |
| 2016 | 7 | Randomized Trial Comparing A Web-Mediated Follow-up With Routine Surveillance In Lung Cancer Patients IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The use of web-based monitoring for lung cancer patients is growing in interest because of promising recent results suggesting improvement in cancer and resource utilization … |
FABRICE DENIS et. al. |
| 2016 | 8 | Genomic Analysis Of Immune Cell Infiltrates Across 11 Tumor Types IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Immune infiltration of the tumor microenvironment has been associated with improved survival for some patients with solid tumors. The precise makeup and prognostic relevance of … |
MICHAEL D IGLESIA et. al. |
| 2016 | 9 | Bilateral Oophorectomy And Breast Cancer Risk In BRCA1 And BRCA2 Mutation Carriers IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Whether oophorectomy reduces breast cancer risk among BRCA mutation carriers is a matter of debate. We undertook a prospective analysis of bilateral oophorectomy and breast cancer … |
JOANNE KOTSOPOULOS et. al. |
| 2016 | 10 | The Intestinal Microbiome And Estrogen Receptor-Positive Female Breast Cancer IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The huge communities of residential microbes, including bacteria, viruses, Archaea, and Eukaryotes, that colonize humans are increasingly recognized as playing important roles in … |
Maryann Kwa; Claudia S Plottel; Martin J Blaser; Sylvia Adams; |
| 2015 | 1 | Annual Report To The Nation On The Status Of Cancer, 1975-2011, Featuring Incidence Of Breast Cancer Subtypes By Race/Ethnicity, Poverty, And State IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The American Cancer Society (ACS), Centers for Disease Control and Prevention (CDC), National Cancer Institute (NCI), and North American Association of Central Cancer Registries … |
BETSY A KOHLER et. al. |
| 2015 | 2 | Prediction of Breast Cancer Risk Based on Profiling with Common Genetic Variants IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Data for multiple common susceptibility alleles for breast cancer may be combined to identify women at different levels of breast cancer risk. Such stratification could guide … |
NASIM MAVADDAT et. al. |
| 2015 | 3 | US Assessment Of HPV Types In Cancers: Implications For Current And 9-valent HPV Vaccines IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: This study sought to determine the prevaccine type-specific prevalence of human papillomavirus (HPV)-associated cancers in the United States to evaluate the potential impact of … |
MONA SARAIYA et. al. |
| 2015 | 4 | PDL1 Regulation By P53 Via MiR-34 IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Although clinical studies have shown promise for targeting PD1/PDL1 signaling in non-small cell lung cancer (NSCLC), the regulation of PDL1 expression is poorly understood. Here, … |
MARIA ANGELICA CORTEZ et. al. |
| 2015 | 5 | Primary Tumor Location As A Prognostic Factor In Metastatic Colorectal Cancer IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: We sought to clarify the prognostic impact of primary tumor location in metastatic colorectal cancer (mCRC). We evaluated the association between tumor location and survival … |
FOTIOS LOUPAKIS et. al. |
| 2015 | 6 | Nab-Paclitaxel Plus Gemcitabine For Metastatic Pancreatic Cancer: Long-term Survival From A Phase III Trial IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Positive findings from the phase III MPACT trial led to the regulatory approval of nab-paclitaxel plus gemcitabine as a treatment option for patients with metastatic pancreatic … |
DAVID GOLDSTEIN et. al. |
| 2015 | 7 | Ovarian Cancer Risk After Salpingectomy: A Nationwide Population-based Study IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Recent genetic and morphologic studies have challenged the traditional view on the pathogenesis of ovarian cancer; suggesting that ovarian cancer predominantly arises within the … |
Henrik Falconer; Li Yin; Henrik Grönberg; Daniel Altman; |
| 2015 | 8 | Germline Mutations In The BRIP1, BARD1, PALB2, And NBN Genes In Women With Ovarian Cancer IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy, responsible for 13 000 deaths per year in the United States. Risk prediction based on identifying … |
SUSAN J RAMUS et. al. |
| 2015 | 9 | Adult Weight Gain And Adiposity-related Cancers: A Dose-response Meta-analysis Of Prospective Observational Studies IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Adiposity, measured by body mass index, is implicated in carcinogenesis. While adult weight gain has diverse advantages over body mass index in measuring adiposity, systematic … |
NANA KEUM et. al. |
| 2015 | 10 | Exosome-mediated Transfer Of MicroRNAs Within The Tumor Microenvironment And Neuroblastoma Resistance To Chemotherapy IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: How exosomic microRNAs (miRNAs) contribute to the development of drug resistance in the context of the tumor microenvironment has not been previously described in neuroblastoma … |
KISHORE B CHALLAGUNDLA et. al. |
| 2014 | 1 | Prognostic Role Of Neutrophil-to-lymphocyte Ratio In Solid Tumors: A Systematic Review And Meta-analysis IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Inflammation may play an important role in cancer progression, and a high neutrophil-to-lymphocyte ratio (NLR) has been reported to be a poor prognostic indicator in several … |
ARNOUD J TEMPLETON et. al. |
| 2014 | 2 | US Incidence Of Breast Cancer Subtypes Defined By Joint Hormone Receptor And HER2 Status IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: In 2010, Surveillance, Epidemiology, and End Results (SEER) registries began collecting human epidermal growth factor 2 (HER2) receptor status for breast cancer cases. Breast … |
NADIA HOWLADER et. al. |
| 2014 | 3 | Development Of The National Cancer Institute’s Patient-reported Outcomes Version Of The Common Terminology Criteria For Adverse Events (PRO-CTCAE) IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The standard approach for documenting symptomatic adverse events (AEs) in cancer clinical trials involves investigator reporting using the National Cancer Institute’s (NCI’s) … |
ETHAN BASCH et. al. |
| 2014 | 4 | Circulating Tumor Cells Predict Survival In Early Average-to-high Risk Breast Cancer Patients IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Circulating tumor cells (CTCs) have been shown to predict reduced survival outcomes in metastatic breast cancer. CTCs were analyzed in 2026 patients with early breast cancer … |
BRIGITTE RACK et. al. |
| 2014 | 5 | Television Viewing And Time Spent Sedentary In Relation To Cancer Risk: A Meta-analysis IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Sedentary behavior is emerging as an independent risk factor for chronic disease and mortality. However, the evidence relating television (TV) viewing and other sedentary … |
Daniela Schmid; Michael F Leitzmann; |
| 2014 | 6 | Recommended Patient-reported Core Set Of Symptoms To Measure In Adult Cancer Treatment Trials IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The National Cancer Institute’s Symptom Management and Health-Related Quality of Life Steering Committee held a clinical trials planning meeting (September 2011) to identify a … |
BRYCE B REEVE et. al. |
| 2014 | 7 | Prognostic And Therapeutic Relevance Of Molecular Subtypes In High-grade Serous Ovarian Cancer IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Molecular classification of high-grade serous ovarian cancer (HGSOC) using transcriptional profiling has proven to be complex and difficult to validate across studies. We … |
GOTTFRIED E KONECNY et. al. |
| 2014 | 8 | Crizotinib In Advanced, Chemoresistant Anaplastic Lymphoma Kinase-positive Lymphoma Patients IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Anaplastic lymphoma kinase (ALK)-positive lymphomas respond to chemotherapy, but relapses, which bear a poor prognosis, occur. Crizotinib inhibits ALK in vitro and in vivo and was … |
CARLO GAMBACORTI PASSERINI et. al. |
| 2014 | 9 | Mammographic Density Phenotypes and Risk of Breast Cancer: A Meta-analysis IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Fibroglandular breast tissue appears dense on mammogram, whereas fat appears nondense. It is unclear whether absolute or percentage dense area more strongly predicts breast cancer … |
ANDREAS PETTERSSON et. al. |
| 2014 | 10 | Baseline Selenium Status And Effects Of Selenium And Vitamin E Supplementation On Prostate Cancer Risk IF:4 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The Selenium and Vitamin E Cancer Prevention Trial found no effect of selenium supplementation on prostate cancer (PCa) risk but a 17% increased risk from vitamin E … |
ALAN R KRISTAL et. al. |
| 2013 | 1 | Combining Radiotherapy And Cancer Immunotherapy: A Paradigm Shift IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The therapeutic application of ionizing radiation has been largely based on its cytocidal power combined with the ability to selectively target tumors. Radiotherapy effects on … |
Silvia C Formenti; Sandra Demaria; |
| 2013 | 2 | Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results from Prospective Analysis of EMBRACE IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Reliable estimates of cancer risk are critical for guiding management of BRCA1 and BRCA2 mutation carriers. The aims of this study were to derive penetrance estimates for breast … |
NASIM MAVADDAT et. al. |
| 2013 | 3 | Human Gut Microbiome And Risk For Colorectal Cancer IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: We tested the hypothesis that an altered community of gut microbes is associated with risk of colorectal cancer (CRC) in a study of 47 CRC case subjects and 94 control subjects. … |
JIYOUNG AHN et. al. |
| 2013 | 4 | Impact Of EGFR Inhibitor In Non-small Cell Lung Cancer On Progression-free And Overall Survival: A Meta-analysis IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The epidermal growth factor receptor (EGFR) signaling pathway is crucial for regulating tumorigenesis and cell survival and may be important in the development and progression of … |
CHEE KHOON LEE et. al. |
| 2013 | 5 | An International Ki67 Reproducibility Study IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: In breast cancer, immunohistochemical assessment of proliferation using the marker Ki67 has potential use in both research and clinical management. However, lack of consistency … |
MEI-YIN C POLLEY et. al. |
| 2013 | 6 | A Multigene Expression Assay To Predict Local Recurrence Risk For Ductal Carcinoma In Situ Of The Breast IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: For women with ductal carcinoma in situ (DCIS) of the breast, the risk of developing an ipsilateral breast event (IBE; defined as local recurrence of DCIS or invasive carcinoma) … |
LAWRENCE J SOLIN et. al. |
| 2013 | 7 | Wnt Signaling Pathway In Non-small Cell Lung Cancer IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Wnt/β-catenin alterations are prominent in human malignancies. In non-small cell lung cancer (NSCLC), β-catenin and APC mutations are uncommon, but Wnt signaling is important in … |
David J Stewart; |
| 2013 | 8 | Serum MiR-21 As A Diagnostic And Prognostic Biomarker In Colorectal Cancer IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The oncogenic microRNAs (miRNAs) miR-21 and miR-31 negatively regulate tumor-suppressor genes. Their potential as serum biomarkers has not been determined in human colorectal … |
YUJI TOIYAMA et. al. |
| 2013 | 9 | The Clinical Relevance Of Cancer Cell Lines IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Although advances in genomics during the last decade have opened new avenues for translational research and allowed the direct evaluation of clinical samples, there is still a … |
Jean-Pierre Gillet; Sudhir Varma; Michael M Gottesman; |
| 2013 | 10 | Microsatellite Instability And BRAF Mutation Testing In Colorectal Cancer Prognostication IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: BRAF mutation in colorectal cancer is associated with microsatellite instability (MSI) through its relationship with high-level CpG island methylator phenotype (CIMP) and MLH1 … |
PAUL LOCHHEAD et. al. |
| 2012 | 1 | Prostate Cancer Screening In The Randomized Prostate, Lung, Colorectal, And Ovarian Cancer Screening Trial: Mortality Results After 13 Years Of Follow-up IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The prostate component of the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial was undertaken to determine whether there is a reduction in prostate cancer … |
GERALD L ANDRIOLE et. al. |
| 2012 | 2 | Physical Activity, Biomarkers, And Disease Outcomes In Cancer Survivors: A Systematic Review IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Cancer survivors often seek information about how lifestyle factors, such as physical activity, may influence their prognosis. We systematically reviewed studies that examined … |
RACHEL BALLARD-BARBASH et. al. |
| 2012 | 3 | Quality Of Life, Fertility Concerns, And Behavioral Health Outcomes In Younger Breast Cancer Survivors: A Systematic Review IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Breast cancer is the most common cancer in women younger than age 50 years. Cancer treatments in younger women may cause premature menopause, infertility, and negative … |
Jessica Howard-Anderson; Patricia A Ganz; Julienne E Bower; Annette L Stanton; |
| 2012 | 4 | Risk Of Heart Failure In Breast Cancer Patients After Anthracycline And Trastuzumab Treatment: A Retrospective Cohort Study IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Clinical trials demonstrated that women treated for breast cancer with anthracycline or trastuzumab are at increased risk for heart failure and/or cardiomyopathy (HF/CM), but the … |
ERIN J AIELLO BOWLES et. al. |
| 2012 | 5 | TNM Staging Of Neoplasms Of The Endocrine Pancreas: Results From A Large International Cohort Study IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Both the European Neuroendocrine Tumor Society (ENETS) and the International Union for Cancer Control/American Joint Cancer Committee/World Health Organization (UICC/AJCC/WHO) … |
G RINDI et. al. |
| 2012 | 6 | Diabetes And Cardiovascular Disease During Androgen Deprivation Therapy: Observational Study Of Veterans With Prostate Cancer IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details |
Nancy L Keating; A James O’Malley; Stephen J Freedland; Matthew R Smith; |
| 2012 | 7 | Fifteen-year Effects Of Helicobacter Pylori, Garlic, And Vitamin Treatments On Gastric Cancer Incidence And Mortality IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: In the Shandong Intervention Trial, 2 weeks of antibiotic treatment for Helicobacter pylori reduced the prevalence of precancerous gastric lesions, whereas 7.3 years of oral … |
JUN-LING MA et. al. |
| 2012 | 8 | Effect Of KRAS Oncogene Substitutions On Protein Behavior: Implications For Signaling And Clinical Outcome IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Mutations in the v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) play a critical role in cancer cell growth and resistance to therapy. Most mutations occur at codons … |
NATHAN T IHLE et. al. |
| 2012 | 9 | CYP2D6 Genotype And Tamoxifen Response In Postmenopausal Women With Endocrine-responsive Breast Cancer: The Breast International Group 1-98 Trial IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Adjuvant tamoxifen therapy is effective for postmenopausal women with endocrine-responsive breast cancer. Cytochrome P450 2D6 (CYP2D6) enzyme metabolizes tamoxifen to clinically … |
MEREDITH M REGAN et. al. |
| 2012 | 10 | A Three-gene Model To Robustly Identify Breast Cancer Molecular Subtypes IF:5 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Single sample predictors (SSPs) and Subtype classification models (SCMs) are gene expression-based classifiers used to identify the four primary molecular subtypes of breast … |
BENJAMIN HAIBE-KAINS et. al. |
| 2011 | 1 | Projections Of The Cost Of Cancer Care In The United States: 2010-2020 IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Current estimates of the costs of cancer care in the United States are based on data from 2003 and earlier. However, incidence, survival, and practice patterns have been changing … |
Angela B Mariotto; K Robin Yabroff; Yongwu Shao; Eric J Feuer; Martin L Brown; |
| 2011 | 2 | Assessment of Ki67 in Breast Cancer: Recommendations from The International Ki67 in Breast Cancer Working Group IF:9 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Uncontrolled proliferation is a hallmark of cancer. In breast cancer, immunohistochemical assessment of the proportion of cells staining for the nuclear antigen Ki67 has become … |
MITCH DOWSETT et. al. |
| 2011 | 3 | Sequential Vs. Concurrent Chemoradiation For Stage III Non-small Cell Lung Cancer: Randomized Phase III Trial RTOG 9410 IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The combination of chemotherapy with thoracic radiotherapy (TRT) compared with TRT alone has been shown to confer a survival advantage for good performance status patients with … |
WALTER J CURRAN et. al. |
| 2011 | 4 | Risk Of Malignant Progression In Barrett’s Esophagus Patients: Results From A Large Population-based Study IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Barrett’s esophagus (BE) is a premalignant lesion that predisposes to esophageal adenocarcinoma. However, the reported incidence of esophageal adenocarcinoma in patients with BE … |
SHIVARAM BHAT et. al. |
| 2011 | 5 | Cancer Burden In The HIV-infected Population In The United States IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Effective antiretroviral therapy has reduced the risk of AIDS and dramatically prolonged the survival of HIV-infected people in the United States. Consequently, an increasing … |
MEREDITH S SHIELS et. al. |
| 2011 | 6 | Human Papillomavirus Testing In The Prevention Of Cervical Cancer IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Strong evidence now supports the adoption of cervical cancer prevention strategies that explicitly focus on persistent infection with the causal agent, human papillomavirus (HPV). … |
MARK SCHIFFMAN et. al. |
| 2011 | 7 | Long-term Outcomes Of Invasive Ipsilateral Breast Tumor Recurrences After Lumpectomy In NSABP B-17 And B-24 Randomized Clinical Trials For DCIS IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Ipsilateral breast tumor recurrence (IBTR) is the most common failure event after lumpectomy for ductal carcinoma in situ (DCIS). We evaluated invasive IBTR (I-IBTR) and its … |
IRENE L WAPNIR et. al. |
| 2011 | 8 | Hypertension As A Biomarker Of Efficacy In Patients With Metastatic Renal Cell Carcinoma Treated With Sunitinib IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Hypertension (HTN) is an on-target effect of the vascular endothelial growth factor pathway inhibitor, sunitinib. We evaluated the association of sunitinib-induced HTN with … |
BRIAN I RINI et. al. |
| 2011 | 9 | Once-only Sigmoidoscopy In Colorectal Cancer Screening: Follow-up Findings Of The Italian Randomized Controlled Trial–SCORE IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: A single flexible sigmoidoscopy at around the age of 60 years has been proposed as an effective strategy for colorectal cancer (CRC) screening. We conducted a randomized … |
NEREO SEGNAN et. al. |
| 2011 | 10 | Preventable Exposures Associated With Human Cancers IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Information on the causes of cancer at specific sites is important to cancer control planners, cancer researchers, cancer patients, and the general public. The International … |
VINCENT JAMES COGLIANO et. al. |
| 2010 | 1 | Overdiagnosis In Cancer IF:8 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: This article summarizes the phenomenon of cancer overdiagnosis-the diagnosis of a cancer that would otherwise not go on to cause symptoms or death. We describe the two … |
H Gilbert Welch; William C Black; |
| 2010 | 2 | Protection from Right- and Left-sided Colorectal Neoplasms After Colonoscopy: Population-based Study IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: BACKGROUND Colonoscopy is used for early detection and prevention of colorectal cancer, but evidence on the magnitude of overall protection and protection according to anatomical … |
HERMANN BRENNER et. al. |
| 2010 | 3 | Improved Endpoints For Cancer Immunotherapy Trials IF:7 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Unlike chemotherapy, which acts directly on the tumor, cancer immunotherapies exert their effects on the immune system and demonstrate new kinetics that involve building a … |
AXEL HOOS et. al. |
| 2010 | 4 | Impact Of Human Papillomavirus (HPV)-6/11/16/18 Vaccine On All HPV-associated Genital Diseases In Young Women IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a … |
NUBIA MUÑOZ et. al. |
| 2010 | 5 | Subsequent Neoplasms In 5-year Survivors Of Childhood Cancer: The Childhood Cancer Survivor Study IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: The occurrence of subsequent neoplasms has direct impact on the quantity and quality of life in cancer survivors. We have expanded our analysis of these events in the Childhood … |
DEBRA L FRIEDMAN et. al. |
| 2010 | 6 | Therapy-induced Senescence In Cancer IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Cellular senescence is a response to nonlethal stress that results in persistent cytostasis with a distinct morphological and biochemical phenotype. The senescence phenotype, … |
Jonathan A Ewald; Joshua A Desotelle; George Wilding; David F Jarrard; |
| 2010 | 7 | Long-term Absolute Risk Of Cervical Intraepithelial Neoplasia Grade 3 Or Worse Following Human Papillomavirus Infection: Role Of Persistence IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Infection with high-risk human papillomavirus (HPV) is the main cause of high-grade cervical intraepithelial neoplasia (CIN) and cancer. It has been suggested that information … |
Susanne K Kjær; Kirsten Frederiksen; Christian Munk; Thomas Iftner; |
| 2010 | 8 | Isocitrate Dehydrogenase 1 And 2 Mutations In Cancer: Alterations At A Crossroads Of Cellular Metabolism IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Dysregulation of metabolism is a common phenomenon in cancer cells. The NADP(+)-dependent isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) function at a crossroads of cellular … |
Zachary J Reitman; Hai Yan; |
| 2010 | 9 | Associations Of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From The Breast Cancer Association Consortium Studies IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: Previous studies have suggested that breast cancer risk factors are associated with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors. We … |
XIAOHONG R YANG et. al. |
| 2010 | 10 | Fruit And Vegetable Intake And Overall Cancer Risk In The European Prospective Investigation Into Cancer And Nutrition (EPIC) IF:6 Related Papers Related Patents Related Grants Related Orgs Related Experts Details Abstract: It is widely believed that cancer can be prevented by high intake of fruits and vegetables. However, inconsistent results from many studies have not been able to conclusively … |
PAOLO BOFFETTA et. al. |